March Madness: Round 2 picks

Day One was mostly upset-free, but Day Two made up for it, with two No. 15 seeds taking down their No. 2 matchups (Norfolk State over Missouri; Lehigh over Duke) and plenty of other lower seeds moving on. Here's what to look for in Round 2.

SOUTH
This region had some of the best upsets of the whole tournament, with No. 15 Lehigh moving on, No. 11 Colorado taking down UNLV, No. 12 Virginia Commonwealth (from last year's Final Four) beating Wichita State, and No. 10 Xavier toppling Notre Dame. Will the adrenaline from so many crazy upsets carry into the next round? VCU should have the mettle to keep its head against Indiana, and Xavier (10) and Lehigh (15) will both be facing another team that just came through similar circumstances, but Colorado (11) may be the most likely of the deep seeds to run into reality when it faces the Baylor Bears (3).

Kentucky (1) vs. Iowa State (8): The Wildcats are in it for the long haul and will hold off Iowa State, which knocked off the defending champs, Connecticut.
Virginia Commonwealth (12) vs. Indiana (4): A tough call, with traditionally weak but recently great VCU taking on recently weak but traditionally great Indiana. I pick the Hoosiers.
Colorado (11) vs. Baylor (3): Baylor will end the excitement for Colorado.
Xavier (10) vs. Lehigh (15): Xavier, a strong team that needed a break, gets one and takes advantage by beating Lehigh.

WEST
Not too many surprises in this bracket, until you get to No. 15 Norfolk State upsetting No. 2 Missouri, a pick to win it all for many. Watch out for upsets among some higher seeds that shook the first-round-loss albatross only to run into a tough opponent in the second round (Louisville, Florida).

(1) Michigan State vs. (9) St. Louis: The Spartans continue to roll.
(5) New Mexico vs. (4) Louisville: Except a tighter game in this go-around, but Rick Pitino's Cardinals should be able to slip into the Sweet 16.
(6) Murray State vs. (3) Marquette: Murray State surprised many by making it to this round unscathed, but Marquette should have the depth to handle the upstarts.
(7) Florida vs. (15) Norfolk State: Why not Norfolk State? They had a load of poise down the stretch, and I still don't buy the Gators.

EAST
All the higher seeds won in this region, but that wasn't the news: Syracuse, short its great defensive center Fab Melo, was almost the first No. 1 seed ever to lose, escaping UNC-Asheville by a smidge. The teetering Orange could be looking at a short stay.

(1) Syracuse vs. (8) Kansas State: Syracuse will toughen up and win this round, but no guarantees once the Orange hit the Sweet 16.
(5) Vanderbilt vs. (4) Wisconsin: The Badgers have a clear path to the Elite Eight at this point and should be able to handle Vanderbilt.
(6) Cincinnati vs. (3) Florida State: Florida State, the pride of the ACC, takes care of a strong Bearcats team.
(7) Gonzaga vs. (2) Ohio State: Both teams won their first-round matchups by double digits, but Ohio State as a Final Four contender should take this game.

MIDWEST
This bracket is Upset Village, with No. 12 South Florida cranking past No. 5 Temple, No. 13 Ohio downing No. 4 Michigan, No. 11 N.C. State knocking off No. 6 San Diego State, and No. 10 Purdue pushing past No. 7 St. Mary's. This region has a very good chance of a double-digit seed going deep, although Kansas (2), Georgetown (3), and North Carolina (1) showed they are reading to contest that with double-digit wins. Their paths may have just become easier.

(1) North Carolina vs. (8) Creighton: A Tar Heels romp or a Creighton squeaker? North Carolina is tasting the Elite Eight already.
(12) South Florida vs. (13) Ohio: South Florida cleaned out Temple, but I'm feeling good about Ohio right now.
(11) N.C. State vs. (3) Georgetown: How about the Wolfpack? I'll take another upset.
(10) Purdue vs. (2) Kansas: The Jayhawks have the tendency to choke on the big ones, and the Boilermakers have had their share of disappointments and partial rosters over the last few years with the Robbie Hummel saga. Let's go with Purdue.